An overview of treatment for brain cancer

In brain tumor care, different types of doctors often work together to create a patient’s overall treatment plan that combines different types of treatment. This is called a multidisciplinary team. Your care team may include a variety of other health care professionals, such as physician assistants, nurse practitioners, oncology nurses, social workers, pharmacists, counselors, dietitians, rehabilitation specialists, and others. It is important to have a care team that specializes in caring for people with a brain tumor, which may mean talking with medical professionals beyond your local area to help with diagnosis and treatment planning.
Descriptions of the common types of treatments used for a brain tumor are listed below. Your care plan may also include treatment for symptoms and side effects, an important part of your medical care.
Treatment options and recommendations depend on several factors:
- The size, type, and grade of the tumor
- Whether the tumor is putting pressure on vital parts of the brain
- If the tumor has spread to other parts of the CNS or body
- Possible side effects
- The patient’s preferences and overall health
Some types of brain tumors grow rapidly; other tumors grow slowly. Considering all these factors, your doctor will talk with you about how soon treatment should start after diagnosis.
Treatment options include those described below, such as surgery, radiation therapy, chemotherapy, and targeted therapy.
For a low-grade brain tumor, surgery may be the only treatment needed especially if all of the tumor can be removed. If there is visible tumor remaining after surgery, radiation therapy and chemotherapy may be used. For higher-grade tumors, treatment usually begins with surgery, followed by radiation therapy and chemotherapy. Your exact treatment plan will be made by your health care team.
Successfully treating brain tumors can be challenging. The body’s blood-brain barrier normally protects the brain and spinal cord from harmful chemicals. However, this barrier also keeps out many types of chemotherapy. Surgery can be difficult if the tumor is near a delicate part of the brain or spinal cord. Even when the surgeon can completely remove the original tumor, parts of the tumor may remain that are too small to be seen or removed during surgery. Radiation therapy can also damage healthy tissue.
However, research in the past 20 years has helped to significantly lengthen the lives of many people with a brain tumor. More refined surgeries, a better understanding of the types of tumors that respond to chemotherapy and other drugs, and more targeted delivery of radiation therapy have lengthened lives and improved the quality of life for many people diagnosed with a brain tumor.
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